Selected PRS: PGS000020
Selected trait(s): Glucose, HbA1c, T2D
Selected genetic sex: All
Selected genetic ancestry: All

PRS Variant QC Breakdown

Percentages in the table are based on the total number of variants listed in the Original column.

PRS Original MissingIDInScoreFile NoLiftover AlleleMismatch MissingInSG10K CallRate<0.95 HWEpval<1e-6 Final
PGS000020 7502 0 (0.0%) 3 (0.0%) 12 (0.2%) 7 (0.1%) 457 (6.1%) 1277 (17.0%) 5820 (77.6%)

PRS Distribution in SG10K_Health

By genetic ancestry:

By genetic ancestry and cohort:

T2D case-control distribution plot (by genetic ancestry):

T2D case-control distribution plot (by genetic ancestry and cohort):

Meta Analysis of PRS

Trait 1: Glucose
Model: glm(Glucose ~ Age + Genetic Sex + PGS000020)
Overall:
By genetic ancestry:
By genetic ancestry and cohort:
Within Chinese population:
Within Indian population:
Within Malay population:
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Trait 2: HbA1c
Model: glm(HbA1c ~ Age + Genetic Sex + PGS000020)
Overall:
By genetic ancestry:
By genetic ancestry and cohort:
Within Chinese population:
Within Indian population:
Within Malay population:
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Trait 3: T2D
Model: glm(T2D ~ Age + Genetic Sex + PGS000020)
Overall:
By genetic ancestry:
By genetic ancestry and cohort:
Within Chinese population:
Within Indian population:
Within Malay population:
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